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Table 6 ANOVA results for Response 2: PA

From: Experimental design approach, screening and optimization of system variables, analytical method development of flurbiprofen in nanoparticles and stability-indicating methods for high-pressure liquid chromatography

Source

Sum of squares

d. f

Mean square

F-value

p-value

 

Model

2.343E + 06

9

2.604E + 05

3702.47

 < 0.0001

significant

A-Flow rate

2.338E + 06

1

2.338E + 06

33,252.12

 < 0.0001

 

B-Temp

0.9384

1

0.9384

0.0133

0.9094

 

C-Methanol

143.88

1

143.88

2.05

0.1707

 

AB

73.76

1

73.76

1.05

0.3201

 

AC

0.5985

1

0.5985

0.0085

0.9276

 

BC

3.71

1

3.71

0.0527

0.8211

 

A2

4695.79

1

4695.79

66.78

 < 0.0001

 

B2

0.7467

1

0.7467

0.0106

0.9191

 

C2

10.52

1

10.52

0.1495

0.7038

 

Residual

1195.45

17

70.32

   

Cor Total

2.344E + 06

26