Table 3 Lipinski’s rule of five for ADME analysis of the investigated compounds
No. | Name | M.wt | Lipophilicity | Hydrogen Bond Donors | Hydrogen Bond Acceptors | No. of Rule Violations | Drug-Likeness |
|---|---|---|---|---|---|---|---|
Lipinski’s rule limits | Less than 500 Dalton | Less than 5 | Less than 5 | Less than 10 | Less than 2 Violations | Lipinski’s rule Follows | |
1 | Levomenol | 222.37 | 3.56 | 1 | 1 | 0 | Yes |
2 | Nerolidol | 222.37 | 3.86 | 1 | 1 | 0 | Yes |
3 | trans-2-Caren-4-ol | 152.23 | 2.30 | 1 | 1 | 0 | Yes |