Future Journal of Pharmaceutical Sciences

Table 2 Determination of PSE and LOR in the laboratory-prepared mixtures by the proposed spectrophotometric methods

From: Spectral analysis of overlapped absorption bands of binary mixtures—an application on combination of pseudoephedrine sulphate and loratadine mixture

%Recovery^a ± SD
LOR:PSE		PSE						LOR
Ratio	Concentrations (μg/mL)	IAM	AC (256.8 nm)	DW	IDW	RD	D⁰ at 256.8 nm^c (SS)	IAM	CM		D⁰ at 280 nm^d
Ratio	Concentrations (μg/mL)	IAM	AC (256.8 nm)	DW	IDW	RD	D⁰ at 256.8 nm^c (SS)	IAM	D⁰ at 280 nm	D⁰ at 250 nm	D⁰ at 280 nm^d
(1:24)^b	10:240	99.43	99.52	100.07	99.83	100.26	101.23	100.58	101.28	99.75	100.20
(1:12)	15:180	99.18	100.57	100.14	99.79	100.13	100.54	100.78	99.24	100.31	100.12
(1:18)	10:180	99.70	99.87	100.12	100.31	100.10	100.34	100.55	100.67	100.07	100.20
(1:30)	20:600	101.15	99.69	99.41	100.09	99.99	101.03	100.64	101.35	100.35	100.84
(1:48)	5:240	99.92	100.76	100.00	100.07	100.02	100.43	99.75	100.77	100.65	99.25
Mean ± SD		99.88 ± 0.76	100.08 ± 0.55	99.95 ± 0.31	100.02 ± 0.21	100.10 ± 0.11	100.71 ± 0.39	100.46 ± 0.41	100.66 ± 0.85	100.23 ± 0.34	100.12 ± 0.57

^aAverage of three determinations
^bRatio of the cited drugs as in the dosage form
^cDirect measurement of PSE at 256.8 nm after spectrum subtraction of LOR
^dDirect measurement of LOR at 280 nm

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