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Table 2 Determination of the studied drug trimebutine maleate in laboratory-prepared mixtures with its alkali-induced degradation product by the proposed UV-spectrophotometric methods

From: Different aspects in manipulating overlapped spectra used for the analysis of trimebutine maleate and structure elucidation of its degradation products

Concentration (μg/mL)

Percentage of degradation products* (%)

Recovery %

TM

DEG

DW

D2

RD

CC-SS

57.00

3.00

5

99.61

100.56

99.76

99.32

54.00

6.00

10

99.69

100.70

100.30

99.29

48.00

12.00

20

99.79

100.51

100.88

99.65

30.00

30.00

50

99.63

99.93

99.42

100.54

12.00

48.00

80

99.24

99.51

99.34

99.25

9.00

51.00

85

99.55

100.98

99.63

99.19

Mean

99.59

100.37

99.89

99.54

± SD

0.19

0.54

0.59

0.52

  1. *DEG is combined DEG 1 and DEG 2 in the same solution