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Table 2 Determination of the studied drug trimebutine maleate in laboratory-prepared mixtures with its alkali-induced degradation product by the proposed UV-spectrophotometric methods

From: Different aspects in manipulating overlapped spectra used for the analysis of trimebutine maleate and structure elucidation of its degradation products

Concentration (μg/mL)Percentage of degradation products* (%)Recovery %
TMDEGDWD2RDCC-SS
57.003.00599.61100.5699.7699.32
54.006.001099.69100.70100.3099.29
48.0012.002099.79100.51100.8899.65
30.0030.005099.6399.9399.42100.54
12.0048.008099.2499.5199.3499.25
9.0051.008599.55100.9899.6399.19
Mean99.59100.3799.8999.54
± SD0.190.540.590.52
  1. *DEG is combined DEG 1 and DEG 2 in the same solution