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Table 5 Statistical comparison between the obtained results of the analysis of Gast-reg® 100 mg tablets (Batch No. 144695) by the proposed UV-spectrophotometric method and the reported method

From: Different aspects in manipulating overlapped spectra used for the analysis of trimebutine maleate and structure elucidation of its degradation products

ParametersDWD2RDCC-SSReported method [11]**
± SD0.830.520.440.760.68
Student’s t test*0.023 (2.571)*0.001 (2.571)*0.005 (2.571)*0.879 (2.571)* 
F test*1.490 (6.466)*1.71 (6.43)*2.39 (6.43)*1.249 (6.466)*
  1. *The figures in parenthesis are the corresponding theoretical values at p = 0.05
  2. **The reported method used is RP-HPLC for the estimation of trimebutine maleate in tablet dosage form using a mobile phase consisting of 0.02 M ammonium acetate and acetonitrile in a gradient program