Future Journal of Pharmaceutical Sciences

Table 6 Statistical comparison between the obtained results of the proposed UV-spectrophotometric methods and the official method of trimebutine maleate in its pure powdered form

From: Different aspects in manipulating overlapped spectra used for the analysis of trimebutine maleate and structure elucidation of its degradation products

Parameters	DW	D²	RD	CC-SS	Official method [1]**
Mean	99.97	100.36	99.90	100.15	99.73
± SD	0.40	0.58	0.42	0.45	0.86
n	7	7	7	7	4
Variance	0.1600	0.3364	0.1764	0.2025	0.7396
Student’s t test*	0.990 (2.262)*	0.249 (2.262)*	0.726 (2.262)*	0.413 (2.262)*
F test*	4.62 (5.07)*	2.20 (5.07)*	4.19 (5.07)*	3.65 (5.07)*

*The figures in parenthesis are the corresponding theoretical values at p = 0.05
**The official method used is HPLC method using a mobile phase consisting of anhydrous sodium dihydrogen phosphate buffer (pH = 3.0) and acetonitrile in a gradient program

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