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Future Journal of Pharmaceutical Sciences

Table 4 In vitro prothrombin time measurements of aqueous extract in human pooled plasma

From: Antioxidant, anti-inflammatory and anticoagulant activities of three Thymus species grown in southeastern Morocco

In vitro prothrombin time (seconds)

Concentration of a sample in the clotting mixture (μg)

Thymus atlanticus

Thymus zygis

Thymus satureioides

0.35

12.37 ± 0.22

12.15 ± −0.24

12.13 ± 0.25

0.71

12.43 ± 0.27

12.22 ± 0.21

12.20 ± 0.14

1.42

12.77 ± 0.27**

12.28 ± 0.23

12.57 ± 0.12*

2.85

13.13 ± 0.15**

12.72 ± 0.23*

12.62 ± 0.15*

5.7

22.63 ± 1.44***

18.30 ± 0.47***

14.65 ± 0.24***

11.43

56.82 ± 1.59***

46.5 ± 2.59***

34.50 ± 2.04***

Negative control

12.37 ± 0.20

Unfractionated heparin (0.028)

21.88 ± 0.94***

  1. Values are expressed as mean ± SEM of six measurements. T. zygis, T. atlanticus, and T. satureioides vs negative control
  2. *P < 0.05; **P < 0.01; ***P < 0.001
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