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Table 5 Impurity profile of drug using UHPLC-MS/MS

From: Ultra-high performance liquid chromatography-MS/MS (UHPLC-MS/MS) in practice: analysis of drugs and pharmaceutical formulations

Sr. no

Drug(s)

Detection wavelength

Name of impurity/number of impurities detected

References

1

Finasteride

210 nm

4

[154]

2

Famotidine

265 nm

Imines

[155]

3

Desloratadine

280 nm

5

[156]

4

Sitagliptin, vildagliptin, and metformin

210 nm

2

[157]

5

Heroin

–

Acidic and neutral impurity

[158]

6

Dabigatran Etexilate

220 nm

3

[159]

7

Zolmitriptan

–

4

[160]

8

Smokeless powder

210 nm

Nitroglycerin (NG), 2,4-dinitrotoluene (2,4-DNT), and 2,6-dinitrotoluene (2,6-DNT)

[161]

9

Ritonavir

240 nm

13

[162]

10

25-OCH3-PPD

495 nm

3

[163]