Table 6 Permeation flux and apparent permeability coefficient of FNO and its Co-crystal formulation (FNOCC7) (n = 3, mean ± SD)
From: Particle engineering of fenofibrate for advanced drug delivery system
Samples | F, flux (μg/min) | Papp x10-5 (cm/min) | |
|---|---|---|---|
Intestinal non-everted sac | Pure drug | 0.014±0.141 | 3.86±0.167 |
FNOCC7 | 0.322±0.068 | 5.38±0.093 | |