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Table 2 Day-wise comparative healing for medicated hydrogel sheet against standard/control formulation

From: Fabrication and evaluation of a medicated hydrogel film with embelin from Embelia ribes for wound healing activity

Observation day

Standard (Moisturex® cream)/control (blank hydrogel sheet)

Test (medicated hydrogel sheet)

3rd day post treatment

30–40% reduction in wound size and presence of dry scar.

30–40% reduction in wound size. Additionally, absence of dry scar formation, rather the wounds were moist.

6th day post treatment

Absence of epidermis formation.

Formation of a thin epidermis without any scar formation.

9th day post treatment

90% reduction in wound area, but incomplete epidermis formation.

90% reduction in wound area with presence of thick epidermis layer.

12th and 15th day post treatment

Full contraction of the wound area but appearance of non-uniform new skin.

Full contraction of the wound area with appearance of new skin that was uniform, cleaner and healthy.