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Table 3 Apoptotic activity of tested formulations against MDA-MB-231 cells after 48 h treatment

From: Ameliorated in vitro anticancer efficacy of methotrexate d-α-Tocopheryl polyethylene glycol 1000 succinate ester against breast cancer cells

Cell line

Formulation (10 μM)

Viable cells

Early apoptotic

Late apoptotic

Necrotic cells

MDAMB-231

Control

95.57 ± 0.98

0.51 ± 0.18

0.72 ± 0.46

3.2 ± 0.33

MTX

63.23 ± 2.74

21.86 ± 1.0

12.93 ± 2.93

1.97 ± 0.82

MTC

37.90 ± 0.38

2.0 ± 0.13

37.90 ± 0.38

5.37 ± 0.03

  1. Values are mean ± SD (n = 3)