Table 7 Physicochemical characterization of the formulations
Formulation | Appearance | Viscosity (mPas at 40 rpm, 25 °C) | bViscosity (mPas at 40 rpm, 25 °C) | pH at 25 °C | bpH at 25 °C | Osmolality (mOsm/kg) | bOsmolality (mOsm/kg) |
|---|---|---|---|---|---|---|---|
aHAP organogel | Slight yellow gel | 1476 ± 11.32 | 1430 ± 9.65 | 5.9 ± 0.07 | 6.1 ± 0.03 | 450.4 ± 1.01 | 455.5 ± 1.11 |
Optimized HAP organogel | Off white gel | 1402 ± 9.43 | 1411 ± 11.32 | 4.9 ± 0.03 | 4.8 ± 0.07 | 399.1 ± 1.32 | 399.1 ± 1.06 |
Placebo gel (Nonoxynol-9 gel) | Transparent and colorless | 2993 ± 4.99 | 3015 ± 1.03 | 4.2 ± 0.01 | 4.2 ± 0.01 | 91.1 ± 1.28 | 92.2 ± 1.46 |