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Table 7 Physicochemical characterization of the formulations

From: Development of trigger sensitive hyaluronic acid/palm oil-based organogel for in vitro release of HIV/AIDS microbicides using artificial neural networks

FormulationAppearanceViscosity (mPas at 40 rpm, 25 °C)bViscosity (mPas at 40 rpm, 25 °C)pH at 25 °CbpH at 25 °COsmolality (mOsm/kg)bOsmolality (mOsm/kg)
aHAP organogelSlight yellow gel1476 ± 11.321430 ± 9.655.9 ± 0.076.1 ± 0.03450.4 ± 1.01455.5 ± 1.11
Optimized HAP organogelOff white gel1402 ± 9.431411 ± 11.324.9 ± 0.034.8 ± 0.07399.1 ± 1.32399.1 ± 1.06
Placebo gel (Nonoxynol-9 gel)Transparent and colorless2993 ± 4.993015 ± 1.034.2 ± 0.014.2 ± 0.0191.1 ± 1.2892.2 ± 1.46
  1. aHAP organogel (see run 5 in Table 3)
  2. bResults obtained after accelerated stability testing for 3 months