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Table 5 Comparison of predicted and observed experimental values of optimized EZT-SNEDDS (FF1)

From: Application of Box–Behnken design and desirability function in the development and optimization of self-nanoemulsifying drug delivery system for enhanced dissolution of ezetimibe

Response

Predicted value

Observed value

Percent bias (%)*

Y1 (nm)

24.72

26.31 ± 2.64

− 6.04

Y2 (%)

102.64

101.4 ± 3.91

1.22

Y3 (s)

67.99

69.26 ± 2.56

− 1.83

Y4 (%)

49.39

48.74 ± 2.29

1.33

Y5 (%)

97.12

95.38 ± 3.67

1.82

  1. *Percent bias (%) = (predicted value-observed value)/predicted value × 100