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Table 5 Comparison of predicted and observed experimental values of optimized EZT-SNEDDS (FF1)

From: Application of Box–Behnken design and desirability function in the development and optimization of self-nanoemulsifying drug delivery system for enhanced dissolution of ezetimibe

Response Predicted value Observed value Percent bias (%)*
Y1 (nm) 24.72 26.31 ± 2.64 − 6.04
Y2 (%) 102.64 101.4 ± 3.91 1.22
Y3 (s) 67.99 69.26 ± 2.56 − 1.83
Y4 (%) 49.39 48.74 ± 2.29 1.33
Y5 (%) 97.12 95.38 ± 3.67 1.82
  1. *Percent bias (%) = (predicted value-observed value)/predicted value × 100