Identification of validated substitute for Asoka (Saraca asoca (Roxb.) Willd.) by phytochemical and pharmacological evaluations

Future Journal of Pharmaceutical Sciences

Table 3 Effect of test items on uterus weight, on uterine glycogen levels, and on serum lipid profile

Treatment	Organ weights (g)	Uterine glycogen level (%w/w)	Lipid profile
Treatment	Uterus	Uterine glycogen level (%w/w)	Total cholesterol (mg/dl)	Triglycerides (mg/dl)	HDL (mg/dl)
G1: Normal	0.91 ± 0.33	0.52 ± 0.11	100.20 ± 10.38	81.67 ± 7.94	44.67 ± 8.95
G2: Control	0.34 ± 0.05^#	0.38 ± 0.05^#	156.50 ± 11.15^#	121.20 ± 18.06^#	25.50 ± 5.61^#
G3: AB (200 mg/kg, p.o.)	0.80 ± 0.20^*	0.45 ± 0.08	136.50 ± 12.65	84.50 ± 14.79^*	35.17 ± 3.86
G4:AB (400 mg/kg, p.o.)	1.02 ± 0.14^*	0.50 ± 0.09	98.83 ± 14.08^*	79.17 ± 11.00^*	44.50 ± 7.23^*
G5: AS (200 mg/kg, p.o.)	0.36 ± 0.08	0.26 ± 0.05	143.30 ± 14.18	111.70 ± 8.40	28.17 ± 5.84
G6: AS (400 mg/kg, p.o.)	0.99 ± 0.11^*	0.29 ± 0.06	109.20 ± 13.18^*	101.30 ± 9.15^*	41.67 ± 6.71^*
G7: PB (200 mg/kg, p.o.)	0.44 ± 0.14	0.36 ± 0.06	151.00 ± 16.67	106.00 ± 8.02	26.00 ± 8.36
G8: PB (200 mg/kg, p.o.)	0.53 ± 0.14	0.32 ± 0.04	137.70 ± 14.62	106.50 ± 13.55	25.50 ± 5.54
G9: SB (200 mg/kg, p.o.)	0.83 ± 0.17^*	0.30 ± 0.09	113.20 ± 18.12^*	92.83 ± 10.80^*	36.83 ± 6.73
G10: SB (400 mg/kg, p.o.)	1.00 ± 0.09^*	0.32 ± 0.06	102.70 ± 14.61^*	82.17 ± 8.65^*	40.50 ± 9.00^*
G11: TB (200 mg/kg, p.o.)	0.47 ± 0.12	0.32 ± 0.07	149.20 ± 10.57	104.80 ± 10.25	28.67 ± 10.27
G12: TB (200 mg/kg, p.o.)	0.59 ± 0.12	0.34 ± 0.05	153.00 ± 8.19	107.00 ± 10.35	25.00 ± 6.54

Values are mean ± SD, n = 6, ^#p < 0.05 when compared to GP1 normal and *p < 0.05 when compared to GP-2 control by ANOVA followed by Dunnett’s post-test