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Table 7 Results of forced degradation studies

From: An effective stability indicating RP-HPLC method for simultaneous estimation of Dolutegravir and Lamivudine in bulk and their tablet dosage form

Stress degradationDegradation %
DolutegravirLamivudine
Acidic degradation2.41
Alkali degradation13.812.8
Oxidative degradation17.59
Thermal degradation21
  1. Percentage degradation was less than 20% with different stress conditions