Future Journal of Pharmaceutical Sciences

Table 2 Linearity study of Dicyclomine HCl and Simethicone

From: Simultaneous estimation for Dicyclomine HCl and Simethicone in bulk and oral liquid drop formulation: an RP-HPLC method development and validation

S. no.	Dicyclomine HCl			Simethicone
S. no.	Conc. (μg/ml)	AUC	Relative peak area	Conc. (μg/ml)	AUC	Relative peak area
1	5	3772	0.78	5	46,317	3.84
2	10	5292	1.5	10	82,562	7.63
3	15	6855	2.24	15	115,930	11.12
4	20	8413	2.97	20	149,872	14.67
5	25	9972	3.71	25	183,292	18.17
6	30	11,533	4.45	30	218,821	21.88
7	35	13,091	5.18	35	260,412	26.23
8	40	14,954	6.06	40	295,971	29.95
r²			0.9995	0.9991
Slope			0.1494×	0.7418
Intercept at Y axis			0.0007	− 0.0039

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