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Table 4 Antibacterial activity of CoCl2.6H2O, ligands, metal complexes, and reference antibiotic

From: Mono and binuclear cobalt(II) mixed ligand complexes containing 1,10-phenanthroline and adenine using 1,3-diaminopropane as a spacer: synthesis, characterization, and antibacterial activity investigations

 

Antimicrobial activity ( mean IZ diameter (mm) ± SD)

Compound

Escherichia coli

Salmonella typhus

Staphylococcus aurous

Staphylococcus epidermis

CoCl2.6H2O

10.50 ± 0.00

11.33 ± 0.58

12.08 ± 1.01

13.92 ± 0.14

L1

27.33 ± 0.57

35.33 ± 0.28

34.83 ± 0.29

27.28 ± 0.29

L2

0

0

0

0

L3

40.00 ± 0.00

50.17 ± 0.29

54.50 ± 0.50

43.92 ± 0.14

[Co2(L1)4(L2)2(L3)]Cl4

23.76 ± 0.57

23.92 ± 0.14

23.25 ± 0.66

22.50 ± 1.32

[Co(L1)2(L2)(H2O)]Cl2

21.33 ± 0.57

20.50 ± 0.00

19.53 ± 0.50

20.17 ± 0.29

[Co(L1)2(H2O)2]Cl2

20.67 ± 0.57

19.50 ± 0.50

18.67 ± 0.58

19.25 ± 0.43

Methanol

42.75 ± 0.25

42.67 ± 0.58

44.83 ± 0.29

40.83 ± 0.29

Water

0

0

0

0

Ciprofloxacin

35.25 ± 0.25

40.50 ± 0.50

29.92 ± 0.38

36.08 ± 1.01