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Table 2 Effect of analytical development coefficients

From: A Design of Experiment (DoE) based approach for development and optimization of nanosuspensions of telmisartan, a BCS class II antihypertensive drug

Effect of coefficients on retention time

Term

Coefficient estimate

df

Standard error

95% CI low

95% CI high

VIF

Intercept

2.16

1

0.031

2.08

2.23

 

A-FR

− 0.17

1

0.031

− 0.25

− 0.100

1.00

B-pH

0.51

1

0.031

0.44

0.58

1.00

Effect of coefficients on USP plate count

Intercept

2522.01

1

17.52

2480.59

2563.44

 

A-FR

63.74

1

17.52

105.16

22.31

1.00

B-pH

129.72

1

17.52

171.15

88.30

1.00