Table 5 Factorial design layout
S No. | Combination | X1 (HPMC E15) (mg) | X2 (SPEED) (rpm) | Particle size (nm) | Cumulative percentage drug release (%) |
|---|---|---|---|---|---|
1 | 1 | 0.5 | 1500 | 373.3 | 93.3 |
2 | X1 | 1 | 1500 | 243.9 | 102.4 |
3 | X2 | 0.5 | 2000 | 339.3 | 86.6 |
4 | X1X2 | 1 | 2000 | 433.9 | 100.4 |
5 | midpoint | 0.75 | 1750.0 | 565.6 | 90.8 |
6 | midpoint | 0.75 | 1750.0 | 566.6 | 91.5 |
7 | midpoint | 0.75 | 1750.0 | 560.1 | 92.1 |
8 | midpoint | 0.75 | 1750.0 | 560.5 | 90.7 |