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Table 8 ANOVA table for drug release

From: A Design of Experiment (DoE) based approach for development and optimization of nanosuspensions of telmisartan, a BCS class II antihypertensive drug

Source

Sum of squares

df

Mean square

F value

p value

 

Model

229.51

3

76.50

66.01

< 0.0001

Significant

 A-HPMC E15

187.21

1

187.21

161.54

< 0.0001

 B-Speed

32.40

1

32.40

27.96

0.0011

 AB

9.90

1

9.90

8.54

0.0222

 Curvature

56.12

1

56.12

48.42

0.0002

Pure error

8.11

7

1.16

  

Cor total

293.75

11