Table 3 Solubility of gliclazide in oil, surfactant, and co-surfactant
Sr. no. | Vehicle | Gliclazide solubility* (mg/ml) |
|---|---|---|
1 | Capmul MCM C8 EV | 97.31 ± 6.12 |
2 | Oleic acid | 25.53 ± 8.79 |
3 | Miglyol | 23.29 ± 6.46 |
4 | Ethyl oleate | 3.20 ± 0.19 |
5 | Captex | 2.04 ± 1.03 |
6 | Isopropyl myristate | 1.40 ± 0.97 |
7 | Tween 80 | 96.6 ± 9.01 |
8 | Tween 20 | 7.26 ± 1.79 |
9 | Propylene glycol | 6.7 ± 2.63 |
10 | PEG 400 | 15.8 ± 2.14 |
11 | PEG 600 | 11.12 ± 1.98 |