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Table 1 Interpretation of the Combination index [16, 17]

From: Hesperetin alleviates doxorubicin-induced migration in 4T1 breast cancer cells

CI value

Interpretation

< 0.1

Very strong synergism

0.1–0.3

Strong synergism

0.3–0.7

Synergism

0.7–0.9

Moderate to slight synergism

0.9–1.1

Nearly additive

1.1–1.45

Slight to moderate antagonism

1.45–3.3

Antagonism

> 3.3

Strong to very strong antagonism