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Table 1 Interpretation of the Combination index [16, 17]

From: Hesperetin alleviates doxorubicin-induced migration in 4T1 breast cancer cells

CI valueInterpretation
< 0.1Very strong synergism
0.1–0.3Strong synergism
0.3–0.7Synergism
0.7–0.9Moderate to slight synergism
0.9–1.1Nearly additive
1.1–1.45Slight to moderate antagonism
1.45–3.3Antagonism
> 3.3Strong to very strong antagonism