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Table 4 List of drugs formulated as solid/liquid self-nano emulsified drug delivery systems (SNEDDS)

From: Amelioration of lipophilic compounds in regards to bioavailability as self-emulsifying drug delivery system (SEDDS)

Drug

Oils

Surfactant/co-surfactant

Formualtion type

Therapeutic outcome

Ref.

Naringenin

Triacetin

Tween 80/transcutol P

Self-nanoemulsifying drug delivery system

Improve oral bioavailability

[1]

Talinolol

Triacetin, Miglyol 812, castor oil, isopropyl myristate, soybean oil, and olive oil

Span 20, Span 80, Labrafac PG, Plurol Oleique, and Lauroglycol 90/ethanol, PEG 200, PEG 400, propylene glycol

Self-nanoemulsifying drug delivery system (SNEDDS)

Improved permeability of drug

[7]

Glyburide

Miglyol 812, Ethyl oleate

Tween 80, Cremophore RH 40/1,2-pranpanediol, PEG 400

Self-nanoemulsifying drug delivery system

Improved oral bioavailability

[20]

Atazanavir

Maisine 35-1

Transcutol P and Span 20

Self-nanoemulsifying drug delivery system

Enhance oral bioavailability

[29]

β-carotene

Corn oil, orange oil

Tween 80

Nanoemulsion-based delivery systems formed by spontaneous emulsification

β-carotene bioaccessibility increased due to greater solubilization in mixed micelles

[85]

Resveratrol

Imwitor

Transcutol, Tween 80

Nanoemulsion-based delivery systems formed by spontaneous emulsification

Developed a method which can measure the emulsification of SEDDS

[86]