Fig. 1
From: Light-controlled calcium signalling in prostate cancer and benign prostatic hyperplasia
Regulation of downstream signalling cascade of different biomarkers responsible for prostate cancer or benign prostatic hyperplasia. Ca2+ calcium channel; TRPM2 transient receptor potential cation channel, subfamily M, member 2; cAMP cyclin adenine monophosphate; TRP transient receptor potential; TRPV2 transient receptor potential cation channel, subfamily V, member 2; CXCL5 C-X-C motif chemokine ligand-5; HDAC histone deacetylase; DNMTase DNA methyltransferases; TGFβ1 transforming growth factor; CXCL5 C-X-C motif chemokine ligand-5; DAG diacylglycerol; IP3 inositol-1,4,5-trisphosphate; VDR vitamin D receptor. Significant stimulation (blue arrow). Partial stimulation (dashed blue arrow)