Table 2 Physicochemical characteristics—size, PDI, zeta potential, entrapment efficiency, and assay of zotepine loaded solid lipid nanoparticle formulations (mean ± SD, n = 3)
Formulation | Size (nm) | PDI | ZP (mV) | Assay (mg) | EE (%) |
|---|---|---|---|---|---|
F1 | 104.3 ± 2.4 | 0.17 ± 0.01 | − 30.5 ± 2.5 | 9.8 ± 0.3 | 98.4 ± 2.8 |
F2 | 121.7 ± 3.1 | 0.21 ± 0.06 | − 29.8 ± 1.4 | 9.5 ± 0.4 | 97.3 ± 1.6 |
F3 | 147.3 ± 2.8 | 0.61 ± 0.05 | − 10.6 ± 0.6 | 9.8 ± 0.6 | 96.1 ± 3.2 |
F4 | 259.2 ± 1.6 | 0.34 ± 0.03 | − 28.4 ± 1.7 | 9.6 ± 0.5 | 91.1 ± 1.5 |
F5 | 340.4 ± 3.0 | 0.29 ± 0.07 | − 29.4 ± 2.1 | 8.9 ± 0.1 | 93.1 ± 1.8 |
F6 | 303.3 ± 2.1 | 0.50 ± 0.08 | − 16.6 ± 1.0 | 8.7 ± 0.4 | 91.4 ± 2.1 |