Table 4 Stability studies of optimized formulation of ZT-SLN (F1) at both room temperature (25 °C) and refrigerated (4 °C) for a period 2 months (mean ± SD, n = 3)
Time (day) | At room temperature (25oC) | At refrigerated temperature (4oC) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Size (nm) | PDI | ZP | EE | Assay | Size (nm) | PDI | Potential | EE | Assay | |
1 | 104.3 ± 2.4 | 0.17 ± 0.01 | − 30.5 ± 2.5 | 9.8 ± 0.3 | 98.4 ± 2.8 | 105.1 ± 2.0 | 0.17 ± 0.01 | − 30.8 ± 2.2 | 9.9 ± 0.2 | 98.1 ± 2.3 |
30 | 110.3 ± 3.1 | 0.18 ± 0.03 | − 29.4 ± 1.9 | 9.8 ± 0.5 | 97.4 ± 3.0 | 107.5 ± 1.8 | 0.17 ± 0.06 | − 30.4 ± 1.9 | 9.9 ± 0.2 | 98.4 ± 2.8 |
60 | 114.7 ± 2.7 | 0.19 ± 0.04 | − 28.1 ± 3.1 | 9.7 ± 0.4 | 97.1 ± 1.9 | 108.3 ± 0.9 | 0.18 ± 0.03 | − 30.1 ± 1.4 | 9.8 ± 0.6 | 97.9 ± 1.7 |