Fig. 3

Mechanism of gel formation and drug release. Reproduced with the permission from Juvekar et al. [6]. Solvent exchange occurs from the polymeric solution. Gel solidification during coagulation of the polymeric solution and simultaneously diffusion of the drug takes place, later than polymeric degradation either by surface erosion or throughout the polymeric matrix system. System with fast phase inversion dynamics implant shows burst release of drug, whereas system with slow phase inversion dynamics, the burst release is not observed