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Table 2 Effect of STV, DTZ, and their combinations on serum enzyme biomarkers in isoproterenol-induced myocardial infarction

From: Evaluation of cardioprotection and bio-efficacy enhancement of stevioside and diltiazem in rats

Treatment Blood serum level (U/L)
AST ALT
Normal control 113.66 ± 2.57 40.79 ± 3.15
ISO control 480.73 ± 11.29*** 190.43 ± 4.74***
DTZ 137.9 ± 2.22***### 107.27 ± 2.90***###
STV 100 157.06 ± 2.25***### 125.33 ± 2.02***###
STV 200 135.60 ± 2.02***### 102.47 ± 3.80***###
STV 100+ DTZ 130.13 ± 2.04**### 75.74 ± 4.75***###οοο
STV 200 + DTZ 106.73 ± 2.52###οοο 49.981 ± 2.45###οοο
  1. Results are expressed as mean ± SEM, n = 8
  2. **P < 0.01
  3. ***P < 0.001 when compared to normal
  4. ###P < 0.001 when compared to ISO control
  5. οοP < 0.01
  6. οοοP < 0.001 when compared to DTZ