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Table 1 Formula for preparing tablets containing metronidazole as model drug using MCC, CPE, PME, and PSV as DC excipients

From: Compaction and tableting properties of composite particles of microcrystalline cellulose and crospovidone engineered for direct compression

 

Formulations

Ingredients

I

II

III

IV

MTZ (40%)

200

200

200

200

MCC (59%)

295

–

–

–

CPE (59%)

–

295

–

–

PME (59%)

–

–

295

–

PSV (59%)

–

–

–

295

SSF (1%)

5

5

5

5

Total (mg)

500

500

500

500

  1. I MCC as DC excipient, II CPE as DC excipient, III PME as DC excipient, IV PSV as DC excipient