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Table 4 Interference of the extracts on antimicrobial drugs

From: Antibiofilm potential of Psidium guajava and Passiflora edulis pulp extracts against Staphylococcus aureus, cytotoxicity, and interference on the activity of antimicrobial drugs

Isolate

Drug disk inhibition zone (alone or combined to extracts) in mm

Ery

Ery+PE

Ery+PG

Cip

Cip+PE

Cip+PG

Gen

Gen+PE

Gen+PG

S. aureus 1

0

0

0

18.5

14

13

15

17Ϯ

16.5

S. aureus 2

0

0

0

18.5

20.5Ϯ

16

14.5

14

13.5

S. aureus 3

0

12

0

23.5

19.5Δ

18

0

0

0

S. aureus 4

0

10

0

20.5

18Δ

17

15.5

16.5

12.5Δ

S. aureus 5

0

13.5

0

21

18Δ

15.5

12.5

18Ϯ

15Ϯ

S. aureus 6

0

14

0

20

18Δ

17

0

16Ϯ

15Ϯ

S. aureus 7

0

11

0

21

16Δ

14.5

14.5

12.5Δ

14

S. aureus 8

0

15

0

32

20Δ

18

29

15.5Δ

14.5Δ

S. aureus 9

0

15

0

25.5

20Δ

17.5

19

16.5Δ

15.5Δ

S. aureus 10

0

0

0

23.5

20Δ

14

15

16.5

10.5Δ

  1. Values without any symbol are indifferent when comparing to the control.
  2. +PE addition of P. edulis extract at the MBC, +PG addition of P. guajava extract at the MBC, Ery erythromycin, Cip ciprofloxacin, Gen gentamicin
  3. Statistically significant synergism
  4. ϮTendency of synergism
  5. Statistically significant antagonism
  6. ΔTendency of antagonism