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Table 4 Interference of the extracts on antimicrobial drugs

From: Antibiofilm potential of Psidium guajava and Passiflora edulis pulp extracts against Staphylococcus aureus, cytotoxicity, and interference on the activity of antimicrobial drugs

Isolate Drug disk inhibition zone (alone or combined to extracts) in mm
Ery Ery+PE Ery+PG Cip Cip+PE Cip+PG Gen Gen+PE Gen+PG
S. aureus 1 0 0 0 18.5 14 13 15 17Ϯ 16.5
S. aureus 2 0 0 0 18.5 20.5Ϯ 16 14.5 14 13.5
S. aureus 3 0 12 0 23.5 19.5Δ 18 0 0 0
S. aureus 4 0 10 0 20.5 18Δ 17 15.5 16.5 12.5Δ
S. aureus 5 0 13.5 0 21 18Δ 15.5 12.5 18Ϯ 15Ϯ
S. aureus 6 0 14 0 20 18Δ 17 0 16Ϯ 15Ϯ
S. aureus 7 0 11 0 21 16Δ 14.5 14.5 12.5Δ 14
S. aureus 8 0 15 0 32 20Δ 18 29 15.5Δ 14.5Δ
S. aureus 9 0 15 0 25.5 20Δ 17.5 19 16.5Δ 15.5Δ
S. aureus 10 0 0 0 23.5 20Δ 14 15 16.5 10.5Δ
  1. Values without any symbol are indifferent when comparing to the control.
  2. +PE addition of P. edulis extract at the MBC, +PG addition of P. guajava extract at the MBC, Ery erythromycin, Cip ciprofloxacin, Gen gentamicin
  3. Statistically significant synergism
  4. ϮTendency of synergism
  5. Statistically significant antagonism
  6. ΔTendency of antagonism