Table 10 Forced degradation study results for lamivudine
S.No | Sample name | % assay | % degradation | Purity angle | Purity threshold | Purity flag |
|---|---|---|---|---|---|---|
1 | Controlled sample | 100.1 | -- | 0.310 | 1.375 | No |
2 | Acid degradation | 95.1 | 5.0 | 0.325 | 0.463 | No |
3 | Alkaline degradation | 96.9 | 3.2 | 0.575 | 1.081 | No |
4 | Peroxide degradation | 94.8 | 5.3 | 1.612 | 2.175 | No |
5 | Thermal degradation | 98.3 | 1.8 | 0.268 | 0.294 | No |
6 | UV degradation | 99.7 | 0.4 | 0.318 | 0.335 | No |
7 | Water degradation | 98.4 | 1.7 | 0.264 | 0.298 | No |