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Table 10 Forced degradation study results for lamivudine

From: A new validated stability-indicating RP-HPLC method for simultaneous quantification of dolutegravir and lamivudine in bulk and pharmaceutical dosage form

S.No Sample name % assay % degradation Purity angle Purity threshold Purity flag
1 Controlled sample 100.1 -- 0.310 1.375 No
2 Acid degradation 95.1 5.0 0.325 0.463 No
3 Alkaline degradation 96.9 3.2 0.575 1.081 No
4 Peroxide degradation 94.8 5.3 1.612 2.175 No
5 Thermal degradation 98.3 1.8 0.268 0.294 No
6 UV degradation 99.7 0.4 0.318 0.335 No
7 Water degradation 98.4 1.7 0.264 0.298 No