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Table 1 Retardation factors of p-, m-, and o-nitrophenol, and R(−)-, S(+)-ibuprofen developed on SC-2P/Cu2+ TLC plates using different mobile phase systems (MPs)

From: A new bonded silica based on an amino acid derivative as a TLC stationary phase to solve nitrophenol structural isomerism and ibuprofen stereoisomerism

Nitrophenols MP-1 MP-2 MP-3 MP-4 MP-5
p-isomerRf 0.09 0.12 0.56 0.28 0.67
m-isomerRf 0.19 0.22 0.86 0.45 0.79
o-isomerRf 0.85 0.91 0.89 0.83 0.87
(±)-Ibuprofen MP-6 MP-7 MP-8 MP-9  
R(−)-ibuprofenRf 0.79 0.59 0.43 0.39  
S(+)-ibuprofenRf 0.82 0.67 0.63 0.54  
  1. MP-1 n-hexane:DCE (50:50), MP-2 n-hexane:DCE (75:25), MP-3 n-hexane:DCE:2-propanol (75:20:5), MP-4 n-hexane:DCE:n-propanol (75:20:5), MP-5 n-hexane:DCE:n-propanol (75:15:10), MP-6 DCE:Acetonitrile (70:30), MP-7 DCE:Acetonitrile (80:20), MP-8 DCE:Acetonitrile (90:10), MP-9 DCE:Acetonitrile (95:5)