Table 2 Evaluation parameters of camptothecin gel formulation
From: Design and characterization of camptothecin gel for treatment of epidermoid carcinoma
Formulation code | |||||
|---|---|---|---|---|---|
Parameter | F1 | F2 | F3 | F4 | F5 |
pH* | 6.71 ± 0.03 | 6.83 ± 0.05 | 6.68 ± 0.02 | 6.81 ± 0.04 | 6.90 ± 0.03 |
Spreadability* (g·cm/s) | 15.81 ± 0.42 | 17.93 ± 0.35 | 20.04 ± 0.53 | 22.16 ± 0.50 | 23.27 ± 0.31 |
Extrudability* (% w/w) | 86.32 ± 0.10 | 85.51 ± 0.12 | 90.45 ± 0.11 | 89.64 ± 0.11 | 88.57 ± 0.13 |
Drug content (% w/w) | 89.12 ± 1.3 | 90.61 ± 1.1 | 96.64 ± 1.2 | 94.31 ± 0.8 | 92.76 ± 1.0 |
% Yield | 93.78 | 95.85 | 96.33 | 96.72 | 97.41 |