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Table 2 Evaluation parameters of camptothecin gel formulation

From: Design and characterization of camptothecin gel for treatment of epidermoid carcinoma

  Formulation code
Parameter F1 F2 F3 F4 F5
pH* 6.71 ± 0.03 6.83 ± 0.05 6.68 ± 0.02 6.81 ± 0.04 6.90 ± 0.03
Spreadability* (g·cm/s) 15.81 ± 0.42 17.93 ± 0.35 20.04 ± 0.53 22.16 ± 0.50 23.27 ± 0.31
Extrudability* (% w/w) 86.32 ± 0.10 85.51 ± 0.12 90.45 ± 0.11 89.64 ± 0.11 88.57 ± 0.13
Drug content (% w/w) 89.12 ± 1.3 90.61 ± 1.1 96.64 ± 1.2 94.31 ± 0.8 92.76 ± 1.0
% Yield 93.78 95.85 96.33 96.72 97.41
  1. *Each value represents mean ± S.D. of three observations