Future Journal of Pharmaceutical Sciences

Table 5 Precision data of tenofovir by proposed methods

From: Novel approaches for determination of antiretroviral reverse transcriptase inhibitor agent in commercial dosage forms by using spectrofluorimetric, first derivative spectrophotometric, and HPLC methods

Method I				Method III
C_real (μg/mL)	Conc.* Found (μg/mL)	%Recov.** ±SD	%RSD	C_real (μg/mL)	Conc.* Found (μg/mL)	%Recov.** ±SD	%RSD
	Intra-day analysis				Intra-day analysis
6.26	6.43	102.64 ± 3.17	3.09	30.00	30.33	101.09 ± 0.79	0.79
9.40	9.95	105.87 ± 1.29	1.22	50.00	48.64	97.28 ± 0.50	0.51
12.53	12.86	102.61 ± 0.57	0.56	70.00	68.82	98.31 ± 0.74	0.75
	Inter-day analysis				Inter-day analysis
Room				Room
6.26	6.28	100.38 ± 0.81	0.80	30.00	29.78	99.25 ± 2.56	2.58
9.40	10.63	113.09 ± 5.52	4.88	50.00	48.13	96.27 ± 1.80	1.87
12.53	13.72	109.52 ± 5.14	4.69	70.00	68.05	97.21 ± 2.17	2.23
Dark				Dark
6.26	7.02	112.15 ± 6.61	5.89	30.00	29.91	99.70 ± 3.19	3.20
9.40	10.56	112.34 ± 5.36	4.77	50.00	49.29	98.58 ± 2.03	2.06
12.53	13.68	109.21 ± 4.59	4.21	70.00	68.48	97.83 ± 2.30	2.36
Refrigerator				Refrigerator
6.26	6.73	107.53 ± 2.37	2.20	30.00	29.43	98.11 ± 2.40	2.45
9.40	10.41	110.74 ± 1.56	1.41	50.00	48.56	97.12 ± 1.23	1.27
12.53	13.39	106.85 ± 1.58	1.48	70.00	68.76	98.23 ± 1.74	1.78

C_real real concentration of the solution, Conc. concentration, Recov. recovery, SD standard deviation, RSD relative standard deviation, RE relative error
*Mean concentration of three determinations
**Mean % recovery of three determinations

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