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Table 3 Effects of EEPM fruits extract on hepatic, renal, and lipid function indices in male rats

From: Antidiabetic effects of P. macrocarpa ethanolic fruit extract in streptozotocin-induced diabetic rats

 

Analyte parameter

Control group

Treated group (5000 mg/kg/b.w)

Ref. values

 

Creatinine mg/dL

0.4 ± 0.02**

0.46 ± 0.03**

0.2-0.8 mg/dL

Renal profile

Phosphorous mg/dL

6.0 ± 0.2*

.05 ± 0.4**

3.1-11 mg/dL

 

HDL cholesterol mg/dL

36.1 ± 2.4*

31.3 ± 1.4*

˃ 27 mg/dL

 

LDL cholesterol mg/dL

32.4 ± 0.8**

30.6 ± 0.3*

˂ 46.8 mg/dL

Lipid profile

Cholesterol mg/dL

71.0 ± 1.7**

68.2 ± 1.2**

40-130 mg/dL

 

Triglyceride mg/dL

75.9 ± 1.4**

76.51 ± 3.3**

60-90 mg/dL

 

ASTU/L

62.5 ± 2.3*

63.08 ± 2.6*

45.7-80.8 U/L

 

ALTU/L

22.7 ± 0.6*

22.05 ± 0.6*

17.5-30.2 U/L

Liver profile

ALPU/L

78.4 ± 1.4*

79.1 ± 0.8**

56.8-128 U/L

 

T.BIL mg/dL

0.3 ± 0.02**

0.3 ± 0.01*

0.20-0.5 mg/dL

 

ALB g/dL

3.9 ± 0.06**

3.9 ± 0.07*

3.8-4.8 g/dL

 

Glu mg/dL

86.8 ± 1.6*

82.0 ± 1.2*

50-135 mg/dL

 

T.Prot g/dL

6.3 ± 0.1**

6.0 ± 0.09**

5.6-7.6 g/dL

  1. AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, T.BIL total bilirubin, ALB albumin, Glu glucose, T.PROT total proteins
  2. *P < 0.05
  3. **P < 0.001 no significantly different from control; n = 6