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Table 4 Effect of EEPM fruits on oral glucose tolerance test

From: Antidiabetic effects of P. macrocarpa ethanolic fruit extract in streptozotocin-induced diabetic rats

Groups, n = 6

Treatment

Blood glucose level (mg/dl) at (min)

0 min

30 min

60 min

90 min

120 min

Normal control

Distilled water

95 ± 2.1

99 ± 2.2

97 ± 2.1

93 ± 2.1

90 ± 2.1

Diabetic control

STZ + untreated

479 ± 7.1

488 ± 7.0

490 ± 7.1

490 ± 7.1

493 ± 7.2

Positive control

STZ + glibenclamide (0.5 mg/kg)

486 ± 3

482 ± 5.2*

476 ± 5.3*

476 ± 3.8

469 ± 4.2**

EEPM

50 mg/kg

478 ± 4.1

480 ± 4.9

478 ± 3

476 ± 3.7

476 ± 5.0*

100 mg/kg

482 ± 4.1

482 ± 4.9

481 ± 5.1

478 ± 6.1*

476 ± 6

200 mg/kg

472 ± 3.1

472 ± 3.1

470 ± 3.5**

469 ± 2.1*

467 ± 3*

  1. *p ˂ 0. 05 represent statistically significant
  2. **p ˂ 0. 01 represent statistically very significant with mean ± SEM, n = 6, when compared with diabetic control by using one-way ANOVA followed by Tukey’s post hoc HSD multiple comparison test