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Table 7 Drug-likeness properties of the designed compounds

From: Computational virtual screening and structure-based design of some epidermal growth factor receptor inhibitors

Molecule MW TPSA WLOGP No. of H-bond donors No. of H-bond acceptors RO5 violations
Molecule 1 588.63 137.48 3.38 3 10 2
Molecule 2 637.1 137.48 4.13 3 11 2
Molecule 3 653.56 137.48 3.98 3 11 2
Molecule 4 655.7 132.44 4.23 4 11 2
Molecule 5 570.64 137.48 2.83 3 6 1
Molecule 6 598.7 137.48 3.46 3 6 1