Table 8 ADME Properties of the designed compounds
Molecule | GI absorption | BBB permeant | Pgp substrate | Bioavailability Score | Synthetic Accessibility |
|---|---|---|---|---|---|
Molecule 1 | Low | No | Yes | 0.17 | 4.22 |
Molecule 2 | Low | No | Yes | 0.17 | 4.88 |
Molecule 3 | Low | No | No | 0.17 | 4.37 |
Molecule 4 | Low | No | No | 0.17 | 4.68 |
Molecule 5 | Low | No | Yes | 0.17 | 4.17 |
Molecule 6 | Low | No | Yes | 0.17 | 4.4 |