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Table 8 ADME Properties of the designed compounds

From: Computational virtual screening and structure-based design of some epidermal growth factor receptor inhibitors

Molecule GI absorption BBB permeant Pgp substrate Bioavailability Score Synthetic Accessibility
Molecule 1 Low No Yes 0.17 4.22
Molecule 2 Low No Yes 0.17 4.88
Molecule 3 Low No No 0.17 4.37
Molecule 4 Low No No 0.17 4.68
Molecule 5 Low No Yes 0.17 4.17
Molecule 6 Low No Yes 0.17 4.4