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Table 4 Effect of methanol extract of S. sparganophora leaves on total protein, malondialdehyde, and reduced glutathione in alloxan-induced hyperglycemic rats

From: Hypoglycemic, antidyslipidemic, and antioxidant activities of methanol extract of Struchium sparganophora leaves in alloxan-induced oxidative stress-mediated diabetes in rats

Group

TP (mg/g tissue)

MDA (nM MDA/mg protein tissue)

GSH (nM GSH/mg protein tissue)

Liver

Kidney

Pancreas

Liver

Kidney

Pancreas

Liver

Kidney

Pancreas

Control

33.06 ± 2.11

35.41 ± 1.48

39.74 ± 0.89

32.97 ± 4.09

45.25 ± 3.73

35.04 ± 2.12

32.26 ± 2.14

42.26 ± 2.14

3.01 ± 0.23

ALO

48.60 ± 9.39a

36.59 ± 2.08

34.18 ± 0.56a

64.75 ± 3.11

75.68 ± 6.11a

40.14 ± 6.01

20.09 ± 4.12a

37.09 ± 4.12

2.05 ± 0.07a

MET

58.39 ± 0.27a,b

35.44 ± 0.50

36.84 ± 0.79a,b

23.53 ± 0.40a,b

61.09 ± 0.08a,b

49.30 ± 0.25a

26.95 ± 1.75b

40.00 ± 2.75

2.77 ± 0.04b

MET + SPA 300

39.91 ± 2.68c

28.18 ± 0.67a,b,c

39.41 ± 0.83b

45.42 ± 5.12a,b,c

49.53 ± 4.44b,c

24.67 ± 0.18b

26.23 ± 3.04a,b

41.23 ± 3.04

3.20 ± 0.35b

SPA 300

31.08 ± 1.15b,c

28.99 ± 2.41a,b,c

41.21 ± 1.07b,c

51.44 ± 5.61a,b,c

44.15 ± 9.25b,c

31.71 ± 0.18c

29.30 ± 3.70b

39.30 ± 3.70

2.85 ± 0.22b

SPA 600

36.46 ± 0.47b,c

31.19 ± 1.89a,b,c

39.70 ± 2.19b,c

52.93 ± 2.49a,b,c

43.21 ± 1.11b,c

39.27 ± 0.94c

33.04 ± 1.08c

43.04 ± 1.08b

3.25 ± 0.29b

  1. Results were expressed in mean ± standard deviation
  2. aSignificant when compared to control at p < 0.05
  3. bSignificant when compared to ALO at p < 0.05
  4. cSignificant when compared to MET at p < 0.05