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Table 5 Effect of methanol extract of S. sparganophora leaves on antioxidant enzymes in alloxan-induced hyperglycemic rats

From: Hypoglycemic, antidyslipidemic, and antioxidant activities of methanol extract of Struchium sparganophora leaves in alloxan-induced oxidative stress-mediated diabetes in rats

Group

CAT (μmol H2O2 consumed/min/mg protein)

SOD (nmol/min/mg protein)

GST (nmol CDNB-GSH/min/mg protein)

Liver

Kidney

Pancreas

Liver

Kidney

Pancreas

Liver

Kidney

Pancreas

Control

23.46 ± 1.30

18.09 ± 1.30

7.64 ± 0.65

43.95 ± 2.06

33.95 ± 2.06

20.47 ± 0.98

43.66 ± 3.30

34.82 ± 3.30

30.82 ± 3.30

ALO

17.31 + 0.97a

15.31 ± 0.97a

5.90 ± 0.70a

27.87 ± 3.22a

30.87 ± 3.22

13.67 ± 1.2a

27.44 ± 2.10a

31.44 ± 4.10

17.44 ± 2.10a

MET

21.95 ± 1.76b

15.95 ± 1.76

6.00 ± 0.65a

33.59 ± 2.11a

30.59 ± 2.11

18.67 ± 2.57b

26.97 ± 3.40a

35.07 ± 3.40

25.07 ± 3.40a,b

MET + SPA 300

22.32 ± 0.55b

18.11 ± 0.55b

6.41 ± 0.21a

33.21 ± 3.41a

31.21 ± 3.41

17.98 ± 1.01b

32.05 ± 0.95a,b

37.00 ± 0.95b

27.00 ± 0.95b

SPA 300

21.04 ± 0.40a,b

17.60 ± 1.40

6.35 ± 0.22a

27.10 ± 3.90a

29.10 ± 3.90

18.03 ± 0.22b

29.03 ± 0.40a

34.03 ± 0.40

20.03 ± 0.40a,c

SPA 600

22.09 ± 1.09b

18.77 ± 1.18c

6.21 ± 0.85a

35.39 ± 2.88a,b

29.39 ± 2.88

17.95 ± 0.58b

37.90 ± 1.74a,b

32.90 ± 1.74

22.90 ± 1.74a,b

  1. Results were expressed in mean ± standard deviation
  2. aSignificant when compared to control at p < 0.05
  3. bSignificant when compared to ALO at p < 0.05
  4. cSignificant when compared to MET at p < 0.05