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Table 5 Results of tablets (products X and Y) analysis by the PCA, DDQ and official methods and their statistical comparison

From: Application of two charge transfer complex formation reactions for selective determination of metformin hydrochloride in pharmaceuticals and urine

Product analyzed Label claim, mg MFH/tablet Founda (percent of label claim ±SD)
Official method PCA method DDQ method
X 500 99.47 ± 1.01 100.21 ± 1.45 99.97 ± 1.79
t = 0.95 t = 0.55
F = 2.06 F = 3.14
Y 500 99.70 ± 1.56 99.51 ± 0.98 100.30 ± 1.17
t = 0.23 t = 0.69
F = 2.53 F = 1.78
  1. aAverage of 5 determinations
  2. ttab and Ftab values for four degrees freedom are 2.77 and 6.39, respectively