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Table 3 Logistic regression analysis of clinical parameters associated with the degree of liver fibrosis in patients infected with HCV genotype 4a

From: Body mass index (BMI) and alpha-fetoprotein (AFP) level correlate with the severity of HCV-induced fibrosis in a cohort of Egyptian patients with chronic HCV

 

Univariate analysis

#Multivariate analysis

p value

OR (95% CI)

p value

OR (95% CI)

Sex (male)

0.240

1.437 (0.785–2.630)

  

Age (years)

0.074

0.967 (0.933–1.003)

  

BMI (kg/m2)

< 0.001***

1.074 (1.040–1.110)

< 0.001***

1.125 (1.070–1.183)

AST (IU/L)

0.493

1.002 (0.997–1.007)

  

ALT (IU/L)

0.212

0.995 (0.988–1.0003)

  

Albumin (g/dL)

< 0.001***

0.237 (0.107–0.523)

0.160

0.401 (0.112–1.436)

Total bilirubin (mg/dL)

0.184

0.614 (0.299–1.261)

  

Direct bilirubin (mg/dL)

0.304

2.320 (0.467–11.537)

  

Blood glucose (mg/dL)

0.530

0.994 (0.977–1.012)

  

AFP (ng/mL)

0.573

1.006 (0.984–1.029)

  

Hb (g/dL)

0.155

0.889 (0.756–1.045)

  

Platelet (103/μL)

0.139

1.003 (0.999–1.007)

  

WBCs (cells/mm3)

0.155

1.000 (1.0–1.0)

  

TSH (IU/L)

0.002**

0.523 (0.349–0.783)

0.005**

0.381 (0.193–0.751)

Creatinine (mg/dL)

0.371

2.114 (0.411–10.873)

  

ALP (IU/L)

0.004**

0.990 (0.983–0.997)

< 0.001***

0.982 (0.974–0.991)

  1. The p value of the comparison between mild and severe groups
  2. #All variables with p < 0.05 were included in the multivariate analysis
  3. *p < 0.05, **p < 0.01, and ***p < 0.001. All p values < 0.05 are shown in bold