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Table 3 Logistic regression analysis of clinical parameters associated with the degree of liver fibrosis in patients infected with HCV genotype 4a

From: Body mass index (BMI) and alpha-fetoprotein (AFP) level correlate with the severity of HCV-induced fibrosis in a cohort of Egyptian patients with chronic HCV

  Univariate analysis #Multivariate analysis
p value OR (95% CI) p value OR (95% CI)
Sex (male) 0.240 1.437 (0.785–2.630)   
Age (years) 0.074 0.967 (0.933–1.003)   
BMI (kg/m2) < 0.001*** 1.074 (1.040–1.110) < 0.001*** 1.125 (1.070–1.183)
AST (IU/L) 0.493 1.002 (0.997–1.007)   
ALT (IU/L) 0.212 0.995 (0.988–1.0003)   
Albumin (g/dL) < 0.001*** 0.237 (0.107–0.523) 0.160 0.401 (0.112–1.436)
Total bilirubin (mg/dL) 0.184 0.614 (0.299–1.261)   
Direct bilirubin (mg/dL) 0.304 2.320 (0.467–11.537)   
Blood glucose (mg/dL) 0.530 0.994 (0.977–1.012)   
AFP (ng/mL) 0.573 1.006 (0.984–1.029)   
Hb (g/dL) 0.155 0.889 (0.756–1.045)   
Platelet (103/μL) 0.139 1.003 (0.999–1.007)   
WBCs (cells/mm3) 0.155 1.000 (1.0–1.0)   
TSH (IU/L) 0.002** 0.523 (0.349–0.783) 0.005** 0.381 (0.193–0.751)
Creatinine (mg/dL) 0.371 2.114 (0.411–10.873)   
ALP (IU/L) 0.004** 0.990 (0.983–0.997) < 0.001*** 0.982 (0.974–0.991)
  1. The p value of the comparison between mild and severe groups
  2. #All variables with p < 0.05 were included in the multivariate analysis
  3. *p < 0.05, **p < 0.01, and ***p < 0.001. All p values < 0.05 are shown in bold