Table 6 Summary of findings in Cryo-TEM analysis
From: Fabrication and characterization of sterically stabilized liposomes of topotecan
Sr. no. | Product name | Group avg. internal volume (nm3) ± SD | % of sphere | % of ellipsoid | Lamellar thickness (nm) | Drug strand thickness n = 300 liposomes (nm) | Unilamellarity | ||
|---|---|---|---|---|---|---|---|---|---|
Avg. | Max. | Min. | |||||||
1 | Topotecan liposome | 40,914 ± 2348 | 100 | 0 | 4.6 | 12.4 ± 0.5 | 26.0 | 7.1 | About 100% |
2 | Placebo liposome | 54,291 ± 2829 | 100 | 0 | 5.3 | NA | NA | NA | About 100% |