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Future Journal of Pharmaceutical Sciences

Table 1 Anxiolytic activity of different extract of A. trilobata on elevated plus-maze test

From: Possible neuropharmacological effects of Adenia trilobata (Roxb.) in the Swiss albino mice model

Group (mg/kg)

Entry into open arm (%)

Control

30.33 ± 0.88

Diazepam (1)

69.33 ± 1.15c

MEATL 200

23.97 ± 0.88ns

MEATL 400

33.85 ± 1.26ns

NFATL 200

25.48 ± 2.95ns

NFATL 400

32.23 ± 2.42a

MEATS 200

22.75 ± 0.87ns

MEATS 400

30.06 ± 0.88ns

NFATS 200

23.14 ± 2.44ns

NFATS 400

41.84 ± 3.19a

  1. ns non-significant; MEATL methanol extract of A. trilobata leaves, NFATL n-hexane fraction of A. trilobata leaves, MEATS methanol extract of A. trilobata stem, NFATS n-hexane fraction of A. trilobata stem
  2. The statistical analysis followed by one-way analysis of variance (Dunnett’s test) compared to the negative control (1% Tween-80) using GraphPad Prism version 8.4
  3. The results were expressed in mean ± SEM (standard error mean)
  4. ap < 0.05 considered as statistically significant
  5. cp < 0.001 considered as statistically significant
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