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Table 1 Anxiolytic activity of different extract of A. trilobata on elevated plus-maze test

From: Possible neuropharmacological effects of Adenia trilobata (Roxb.) in the Swiss albino mice model

Group (mg/kg) Entry into open arm (%)
Control 30.33 ± 0.88
Diazepam (1) 69.33 ± 1.15c
MEATL 200 23.97 ± 0.88ns
MEATL 400 33.85 ± 1.26ns
NFATL 200 25.48 ± 2.95ns
NFATL 400 32.23 ± 2.42a
MEATS 200 22.75 ± 0.87ns
MEATS 400 30.06 ± 0.88ns
NFATS 200 23.14 ± 2.44ns
NFATS 400 41.84 ± 3.19a
  1. ns non-significant; MEATL methanol extract of A. trilobata leaves, NFATL n-hexane fraction of A. trilobata leaves, MEATS methanol extract of A. trilobata stem, NFATS n-hexane fraction of A. trilobata stem
  2. The statistical analysis followed by one-way analysis of variance (Dunnett’s test) compared to the negative control (1% Tween-80) using GraphPad Prism version 8.4
  3. The results were expressed in mean ± SEM (standard error mean)
  4. ap < 0.05 considered as statistically significant
  5. cp < 0.001 considered as statistically significant