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Table 2 Anxiolytic activity of different extract of A. trilobata on hole-board test in mice

From: Possible neuropharmacological effects of Adenia trilobata (Roxb.) in the Swiss albino mice model

Group (mg/kg) No. of head dipping Latency of first head dipping (s)
Control 26.33 ± 0.88 8.33 ± 0.88
Diazepam (1) 64.33 ± 3.16c 2.0 ± 0.57a
MEATL 200 39.33 ± 2.33b 6.33 ± 2.40ns
MEATL 400 51.67 ± 0.88c 5.67 ± 0.88ns
NFATL 200 43.0 ± 2.89c 5.67 ± 1.76ns
NFATL 400 57.67 ± 3.18c 5.33 ± 1.76ns
MEATS 200 31.0 ± 1.53ns 8.0 ± 2.65ns
MEATS 400 40.33 ± 2.33c 7.0 ± 1.53ns
NFATS 200 34.67 ± 0.88ns 7.53 ± 0.33ns
NFATS 400 46.33 ± 1.86c 4.67 ± 0.45ns
  1. ns non-significant, MEATL methanol extract of A. trilobata leaves, NFATL n-hexane fraction of A. trilobata leaves, MEATS methanol extract of A. trilobata stem, NFATS n-hexane fraction of A. trilobata stem
  2. The results were expressed in mean ± SEM (standard error mean)
  3. ap < 0.05 considered as statistically significant
  4. bp < 0.01 considered as statistically significant
  5. cp < 0.001 considered as statistically significant