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Table 2 Biochemical parameters of rats treated with (100, 300, 1000 mg/kg) MA for a period of 28 days

From: Assessment of acute and sub-chronic neurotoxicity of Morus alba L. fruits in rodents

Treatment

Dose (mg/kg, p.o.)

Glucose (mg/dl)

Cholesterol (mg/dl)

AST (U/L)

ALT (IU/L)

Alkaline phosphatase (U/L)

Blood urea nitrogen (mg/dl)

Creatinine (mg/dl)

Total protein (gm/dl)

Albumin (gm/dl)

Control

-

Female

113.78 ± 8.46

77.34 ± 3.38

94.30 ± 7.54

38.68 ± 2.08

53.54 ± 3.06

18.74 ± 1.36

4.22 ± 0.34

7.02 ± 0.46

2.92 ± 0.24

MA

100

110.32 ± 9.60

81.04 ± 3.86

93.66 ± 6.24

40.42 ± 2.16

56.20 ± 2.86

17.92 ± 2.08

3.88 ± 0.30

6.84 ± 0.48

3.10 ± 0.28

MA

300

114.64 ± 7.36

78.54 ± 4.12

90.56 ± 7.92

41.86 ± 1.98

54.82 ± 4.64

18.28 ± 1.62

4.16 ± 0.26

6.78 ± 0.54

2.88 ± 0.32

MA

1000

111.28 ± 8.32

80.46 ± 3.78

93.94 ± 8.60

40.88 ± 2.24

52.80 ± 3.66

19.01 ± 1.28

4.24 ± 0.32

6.88 ± 0.76

2.94 ± 0.34

Control

-

Male

114.12 ± 5.54

54.56 ± 2.68

88.34 ± 5.32

28.38 ± 1.26

93.66 ± 6.54

16.86 ± 1.92

3.60 ± 0.28

6.03 ± 0.32

2.44 ± 0.26

MA

100

112.70 ± 6.72

52.90 ± 3.04

90.04 ± 4.78

26.86 ± 1.80

98.92 ± 7.84

16.44 ± 1.56

3.26 ± 0.24

5.98 ± 0.38

2.56 ± 0.30

MA

300

113.56 ± 4.60

50.46 ± 3.86

89.58 ± 5.82

30.56 ± 1.66

94.92 ± 6.80

15.98 ± 1.36

3.56 ± 0.32

6.12 ± 0.82

2.60 ± 0.42

MA

1000

115.70 ± 7.32

51.52 ± 2.62

87.76 ± 4.68

31.04 ± 1.14

91.26 ± 8.36

16.04 ± 1.60

3.32 ± 0.28

6.10 ± 0.35

2.72 ± 0.38

  1. Values are mean ± SD. There was no significant change in biochemical parameters of rats during treatment
  2. AST aspartate transaminase, ALT alanine transaminase, n = 6