Future Journal of Pharmaceutical Sciences

Table 3 Antidiabetic activity of C. melo fraction and extracts

From: Antidiabetic and antihyperlipidemic activities of Cucumis melo var. momordica fruit extract on experimental animals

Treatment	Dose (mg/kg)	Blood glucose level (mg/dl)
Treatment	Dose (mg/kg)	Day 0	Day 7	Day 14	Day 21	Day 28
Negative control	–	88.83 ± 2.07	102.16 ± 2.18	109.66 ± 2.43	107.16 ± 1.78	76.50 ± 1.05
Positive control	–	299.66 ± 2.59*	287.66 ± 2.44*	287.00 ± 2.11*	288.66 ± 1.65*	279.50 ± 1.69*
References	10	278.50 ± 1.91	181.33 ± 2.29△	144.00 ± 1.4△	107.50 ± 1.4△	76.16 ± 1.68△
CMTF	50	279.16 ± 1.40	235.50 ± 1.34△	200.16 ± 1.64	151.83 ± 1.62△	122.00 ± 1.92△
CMEE 1	400	285.83 ± 1.9	251.83 ± 2.09	214.66 ± 0.88△	178.16 ± 0.98△	160.16 ± 1.62
CMEE 2	200	293.13 ± 0.17	265.16 ± 0.70	230.12 ± 0.32	207.19 ± 0.25	195 ± 0.39
CMAE 1	400	254.35 ± 0.76	255.29 ± 0.14	238.94 ± 0.16	215.89 ± 0.72△	190.69 ± 0.84
CMAE 2	200	278.67 ± 0.13	270.12 ± 0.32	250.31 ± 0.89	235.17 ± 0.54	224.94 ± 0.23

Values are expressed as mean ± standard error of mean (n = 6). *P < 0.05, vs the positive control group; △P < 0.05, vs the negative control group analyzed by one-way ANOVA followed by Tukey’s multiple comparison test
CMTF Cucumis melo toluene fraction (ethanolic extract), CMEE 1 Cucumis melo ethanolic extract (400 mg/kg), CMEE 2 Cucumis melo ethanolic extract (200 mg/kg), CMAE 1 Cucumis melo aqueous extract (400 mg/kg), CMAE 2 Cucumis melo aqueous extract (200 mg/kg)

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