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Table 1 IC50 values for the inhibition of aldose reductase and sorbitol dehydrogenase by selected tropical fruits

From: Carica papaya Linn. fruit extract inhibited the activities of aldose reductase and sorbitol dehydrogenase: possible mechanism for amelioration of diabetic complications

Fruits IC50 (μg/mL)
Aldose reductase Sorbitol dehydrogenase
Apple (Malus domestica) 171.63 ± 5.42a 56.52 ± 4.95a
Banana (Musa paradisiaca) 159.16 ± 5.01b 185.10 ± 13.40b
Pawpaw (Carica papaya) 150.78 ± 4.53b 46.30 ± 1.59a
Watermelon (Citrullus lanatus) 189.13 ± 14.37a 96.60 ± 7.04c
Quercetin 153.85 ± 5.38b 67.50 ± 0.83a
  1. The values are expressed as means ± SEM of triplicate determinations. Means down vertical column not sharing a common letter are significantly different (p < 0.05) from each other