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Table 1 Organoleptic properties and solubility of chondroitin sulfate (CS) and glucosamine sulfate (GlcN). The data represent the qualitative analysis obtained from pharmacy and technical specifications provided by the suppliers (S1 and S2). All methods of performing these analyses were carried out according to the Brazilian pharmacopeia specifications and analytical data from post-marketing [25] and recognized by the Brazilian Health Regulatory Agency (ANVISA), responsible for pharmaceutical product regulation in Brazil [20]

From: Fourier-transformed infrared spectroscopy, physicochemical and biochemical properties of chondroitin sulfate and glucosamine as supporting information on quality control of raw materials

Samples   Pharmacy (S1 samples) Pharmacy (S2 samples) Supplier 1 (S1) Supplier 2 (S1)
Control quality Control quality
CS Organoleptic characteristics White powder; characteristic odor White powder; characteristic odor Fine white amorphous powder, cream or ivory; characteristic odor Powder cream to nearly white amorphous thin ivory, moderately hygroscopic
Solubility Water-soluble Water-soluble Water-soluble Water-soluble
GlcN Organoleptic characteristics Almost white powder Almost white powder White crystalline powder Cream-colored powder almost white
Solubility Soluble in water and practically insoluble in alcohol Soluble in water and practically insoluble in alcohol Easily soluble in water and practically insoluble in ethanol Soluble in water and practically insoluble in acetone, alcohol, and isopropyl alcohol