Baseline | Reperfusion (min) time-point | |||
---|---|---|---|---|
30 | 60 | 120 | ||
LVEDP (mmHg) | ||||
Control | 8.5 ± 1.01 | 33.8 ± 2.3 | 31.2 ± 3.2 | 29.2 ± 2.7 |
HTC | 9.3 ± 1.4 | 43.5 ± 3.6* | 41.7 ± 2.9* | 38.9 ± 3* |
HT+OCT | 8.7 ± 1.5 | 35.3 ± 1.7# | 32 ± 3.7# | 30.8 ± 3.1# |
HT+BRU+OCT | 9.5 ± 1.98 | 41.4 ± 2.5*$ | 40.1 ± 2.7*$ | 37.7 ± 4.9*$ |
LVDP (% of baseline) | ||||
Control | 100 (93.2 ± 8.4 mmHg) | 62.1 ± 2.8 | 50.9 ± 3.4 | 37.2 ± 3.2 |
HTC | 100 (72.2 ± 8.8 mmHg)* | 54.2 ± 3.5* | 43.7 ± 3.1* | 29.5 ± 3.3* |
HT+OCT | 100 (84.2 ± 6.01 mmHg)*# | 63.1 ± 2.8# | 52.3 ± 3.5# | 35.6 ± 4.1# |
HT+BRU+OCT | 100 (75.4 ± 8.3 mmHg)*$ | 53.1 ± 3.3*$ | 42.1 ± 4.1*$ | 28.2 ± 3.8*$ |
Max. dP/dt (% of baseline) | ||||
Control | 100 (2794 ± 121 mmHg/s) | 60.3 ± 3.8 | 49.1 ± 4.8 | 36.6 ± 3.6 |
HTC | 100 (2457 ± 102 mmHg/s)* | 53.8 ± 4.1* | 42.1 ± 4.4* | 28.5 ± 3.6* |
HT+OCT | 100 (2672 ± 160 mmHg/s)*# | 62.1 ± 2.6# | 51.1 ± 2.3# | 37.8 ± 4.9# |
HT+BRU+OCT | 100 (2531 ± 106 mmHg/s)*$ | 52.1 ± 3.2*$ | 41.4 ± 3.2*$ | 29.6 ± 2.9*$ |
Min. dP/dt (% of baseline) | ||||
Control | 100 (2025 ± 199 mmHg/s) | 59.6 ± 3.5 | 47.9 ± 4.4 | 38.2 ± 4.7 |
HTC | 100 (1401 ± 117 mmHg/s)* | 52.4 ± 3.9* | 39.7 ± 3.9* | 28.5 ± 3.6* |
HT+OCT | 100 (1788 ± 124 mmHg/s)*# | 60.1 ± 3.1# | 48.1 ± 4.9# | 36.8 ± 4.6# |
HT+BRU+OCT | 100 (1336 ± 116 mmHg/s)*$ | 50.9 ± 4.4*$ | 38.4 ± 2.9*$ | 27.9 ± 3.7*$ |